Noninvasive mapping of spontaneous fluctuations in tumor oxygenation using F19 MRI
نویسندگان
چکیده
منابع مشابه
Noninvasive quantification of solid tumor microstructure using VERDICT MRI.
There is a need for biomarkers that are useful for noninvasive imaging of tumor pathophysiology and drug efficacy. Through its use of endogenous water, diffusion-weighted MRI (DW-MRI) can be used to probe local tissue architecture and structure. However, most DW-MRI studies of cancer tissues have relied on simplistic mathematical models, such as apparent diffusion coefficient (ADC) or intravoxe...
متن کاملPreoperative Sensorimotor Mapping in Brain Tumor Patients using Spontaneous Fluctuations in Neuronal Activity Imaged with fMRI: Initial Experience
Objective—To describe initial experience with resting state correlation mapping as a potential aid for presurgical planning of brain tumor resections. Methods/Technique—Resting state blood oxygenation dependent (BOLD) fMRI was acquired in seventeen healthy young adults and four patients with brain tumors invading sensorimotor cortex. Conventional fMRI motor mapping (finger tapping protocol) was...
متن کاملSession: Functional Connectivity: MRI Measures of Spontaneous Fluctuations in Intrinsic Networks Title: Spontaneous Signal Fluctuations in Intrinsic Networks
Highlights • Spontaneous hemodynamic fluctuations display spatio-temporal organization. • Task-free fMRI has become a powerful approach for studying properties of large-scale brain networks and their clinical implications. • There remain challenges in interpreting results of task-free fMRI studies, as the neural origins of spontaneous hemodynamic signals are not well understood and fMRI data al...
متن کاملA noninvasive tumor oxygenation imaging strategy using magnetic resonance imaging of endogenous blood and tissue water.
PURPOSE To present a novel imaging strategy for noninvasive measurement of tumor oxygenation using MR imaging of endogenous blood and tissue water. THEORY AND METHODS The proposed approach for oxygen partial pressure (pO2) estimation is based on intravoxel incoherent motion diffusion MRI and the dependence of the blood R2 relaxation rate on the inter-echo spacing measured using a multiple spi...
متن کاملBOLD MRI of human tumor oxygenation during carbogen breathing.
An MRI method is described for demonstrating improved oxygenation of human tumors and normal tissues during carbogen inhalation (95% O2, 5% CO2). T2*-weighted gradient-echo imaging was performed before, during, and after carbogen breathing in 47 tumor patients and 13 male volunteers. Analysis of artifacts and signal intensity was performed. Thirty-six successful tumor examinations were obtained...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Medical Physics
سال: 2010
ISSN: 0094-2405
DOI: 10.1118/1.3484056